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Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling

However, our study was conducted to compare and evaluate cell function from the bulk of FreSHtracer-sorted hES-MSCs, not at the single-cell level, which may cause doubt about the consistency of stem cell quality

A glutathione deficiency can contribute to oxidative stress, which plays a key role in accelerating ageing and the development of many diseases

In that study, UA activated microglia and upregulated autophagy-related proteins such as the LC3II/I ratio, Beclin-1, and LAMP1 in the hippocampus of AD model mice